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Satoru Matsuda | OMICS International
ISSN: 2157-2518

Journal of Carcinogenesis & Mutagenesis
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Satoru Matsuda

Department of Food Science and Nutrition, Kita-Uoya Nishimachi, Nara 630-8506

MAGI Scaffolding Molecules Involved in Cancer Cell Signaling

PTEN is a tumor suppressor gene inactivated in various human cancers, which antagonizes PI3K activity. The PI3K/AKT pathway is frequently activated in cancer, then, the PTEN tumor suppressor may be the major brake of the pathway. Cells that lack functional PTEN gene have constitutively higher levels of PIP3 and activated downstream targets. The PTE... Read More»

Satoru Matsuda and Yasuko Kitagishi

Review Article: J Carcinog Mutagen 2013, S7- 005

DOI: 10.4172/2157-2518.S7-005

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article