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Shizuka Aritomi | OMICS International
ISSN: 2167-1095

Journal of Hypertension: Open Access
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Shizuka Aritomi

Research Center, Ajinomoto Pharmaceuticals, Kanagawa

Cilnidipine, An L-/N-Type Calcium Channel Blocker, Changes the Circulating Angiotensin?(1-7)/Angiotensin II Ratio

Objective:It is well known that cilnidipine, which is a L/N-type calcium channel blocker (CCB), has Angiotensin (Ang) II lowering effects that result in organ protective effects compared to L-type CCBs. However, a recent study indicated that angiotensin-converting enzyme (ACE) 2, which is expressed in the heart and kidney, metabolizes Ang II to Ang... Read More»

Shizuka Aritomi, Kazumi Niinuma, Mai Kawakami, Tarou Nakamura, Tomoyuki Konda, Makoto Shiozaki and Michihiro Yoshimura

Research Article: J Hypertens Open Access 2012, 1: 102

DOI: 10.4172/2167-1095.1000102

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article