Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
Inflammatory Polyneuropathies
Autoimmune-mediated neuropathies result from dysfunction of the immune system triggered by an environmental invading as âimmune-mimicryâ. The immune responses directed towards the
infecting organisms cross-react with components of the peripheral nervous system (PNS). Autoimmune-mediated neuropathies can be classified into acute and chronic categories. The acute inflammatory demyelinating polyneuropathy (AIDP), known as Guillain-Barré syndrome (GBS), and chronic inflammatory demyelinating polyneuropathy (CIDP) are comprised of a number of variants or subtypes. The manifestations of demyelinating and axonal subtypes have been suggested to depend on the primary targets of the immune responses. GBS is characterized by inflammation of nerve roots and peripheral nerves causing acute flaccid paresis with a nadir at 2-4 weeks. An animal model is a useful tool in the study of the pathogenesis and for establishing therapeutic strategies for treatment of the disease. Attempting to create an animal model for GBS has been made over the last 50 years.
- Share this page
Last date updated on June, 2021