A novel detection system for biological agents using Loop-Mediated Isothermal Amplification (LAMP) and an electrochemical DNA chip, Bio Bulwark, has been developed. Genomic DNAs/RNAs roughly extracted from biological agents were amplified by the LAMP method using target-specific primers and strand-displace polymerase. The amplified DNAs were processed to hybridization with the electrochemical DNA chip. Anodic current derived from hoechst 33258, an electrochemically active intercalator, was relative to the amount of the target DNA hybridized with target-specific probes on the DNA chip. All reactions and measurements were conducted using disposable cassettes, which included the reagents for amplification and the DNA chip, and a mobile automatic detection system.
OMICS Group International is one of the leading Open Access Publishers which is running 700+ peer-reviewed journals with quality articles. Journal of Bacteriology & Parasitology is one of the best journals which publish world quality articles. Journal of Bacteriology & Parasitology is a wide range of area that deals with bacterial and parasitic infections.
Last date updated on April, 2024
Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi