alexa Peer Reviewed Journals In Neuronal Marker|OMICS International|Journal Of Molecular Biomarkers And Diagnosis

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Peer Reviewed Journals In Neuronal Marker

Obesity has grown to epidemic proportion throughout the world. Its complications include diabetes, cardiovascular diseases and chronic diseases. However the exact pathophysiology of obesity is still unclear. Excessive food intake seems to play a role in the development of obesity. Role of hypothalamus in the control of food intake has been well-documented. However, human studies on eating behaviors indicated that hypothalamus may receive input from other brain regions, particularly from cortex. Using positron emission tomography (PET) scan, we investigated brain responses (by measurements of regional cerebral blood flow (rCBF), marker of neuronal activity) to the meal stimulations in certain population such as lean, obese subjects, and lean people who has history of severe obese but successfully maintained weight loss (former obese). Results in lean individuals indicated that satiety was associated with increases rCBF in the left dorso-lateral prefrontal cortex (LDLPC). In comparisons of brain responses to a meal between lean and obese individuals, we found that lesser activation in the LDLPFC was observed in obese individual when compared to lean individual regardless of meal size. In addition, normalized neuronal activity in this area has been observed in former obese individuals. In conclusion, differential response of neuronal activity in the LDLPFC may be either an acquired feature of obesity that reverses with successful weight loss or an inherent feature in those people who are able to successfully maintain weight loss. Our findings also indicate that the LDLPFC could be a target for future interventions aimed at modulating eating behavior.(Duc Son Nguyen Trung L, Role of neuronal markers in the pathophysiology of obesity) OMICS Group International is one of the leading Open Access Publishing houses, which has around 700+ peer-reviewed journals, 50,000+ editorial board members, and highly qualified, expert reviewers to meet the objectives of the Peer-Review Process. OMICS Group International peer-review policies are highly appreciated, accepted and adaptable to the criteria that have been prescribed by the international agencies such as NIH, PubMed etc. OMICS Group International also organizes 3000+ International Scientific Conferences per year globally. There is a great deal of information out there on scientific topics. However, whether it can be trusted or not is a key issue at present. The main question that often emerges in this aspect is about the review process adopted to screen the articles for publication. One of the most acceptable and proven process adopted in majority reputed international journals is peer reviewing.
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Last date updated on July, 2014