OMICS Journals refers to the Journals of OMICS Online Publishing Group are engaged in the publishing articles related to the field of genomics, proteomics, glycomics, lipidomics, transcriptomics, metabolomics and ergonomics. The aim of the OMICS Journal focuses on specific research discipline, contributing resourceful and impactful platform to embrace the developments in research with technology. OMICS International has been successful in making its spot in scientific community with 700+ peer-reviewed journals with the support of 50,000+ editorial board members, publishing more than 13000 articles in a year which are accessible to more than 100000 scholars worldwide through World Wide Web. It is also a leading scientific event organizer, organizes over 3000+ International Scientific Conferences all over the world annually with the support from 1000+ Scientific associations.
Molecular profiling refers to the study of specific patterns, or signature, of proteins, mRNA, DNA. Molecular profiling of PTC offers a valuable tool for identifying genes that can be used as diagnostic and prognostic markers. Molecular profiling of papillary thyroid carcinomas samples and paired controls identified 177 differentially expressed genes (98 upregulated and 79 downregulated). The upregulation of potential biomarkers was verified in expanded sample sets by qRT-PCR and immunohistochemisty, and included arachidonic acid 5-lipoxygenase (ALOX5), urokinase plasminogen activator and its receptor (uPA/uPAR) and kallikreins 7 and 10 (KLK7/KLK10). ALOX5 expression was elevated in PTC (22.57 fold) and demonstrated a direct correlation with tumor invasiveness. (Jan Geliebter, Molecular profiling of papillary thyroid cancer identifies functional biomarkers)
Last date updated on July, 2014