alexa Scholarly Open Access Journals In Molecular Marker|OMICS International|Journal Of Molecular Biomarkers And Diagnosis

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Scholarly Open Access Journals In Molecular Marker

New generation diagnostic platforms, like commercially available kits have enabled to measure accurate blood glucose level that predict diabetic condition, helping to define diagnosis and the most appropriate therapies. However, hematological evaluation of specimens obtained from blood of the patients is the gold standard of diagnosis. To demonstrate the biomarkers associated with early diagnosed type 2 diabetes, subjects are carefully selected by measuring the blood glucose HbA1C level at fasting period. Samples from the subjects are ultra-centrifuged to winnow out the large abundant protein like Globulin and Albumin. Low abundant serum proteins are then separated through chromatographic fractional analysis with 2D liquid chromatography based on charge and hydrophobicity. Ultimately for the characterization of molecular marker mass spectroscopic analysis are done. This analysis provides for measurement of the peptide fragment masses generated by trypsin digestion of the protein where the mass resolution is a measure of a spectrometer’s capability to produce separate signals of ions of similar mass. Finally, having obtained the molecular weight, pI, and peptide fingerprints of the molecular markers of interest, identification are accomplished throughout the peptident tool database. (Md. Mahmodul Islam, Assessment of serum based molecular marker creditworthy for early diagnosed type 2 Diabetes) Scholarly open access journals have emerged as an alternative to traditional subscription journals. Open access scholarly journals are available online to the reader without financial, legal, or technical barriers. Scholarly open access journals are journals which are respected for the extensive research and information they provide about the point. The research often possesses refereed meaning that it is reviewed by other scientists who are knowledgeable about the theme of the article. Scholarly open access journals cite their sources using references or bibliographies.
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Last date updated on July, 2014

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