For the drug to get excreted into urine or bile it has to undergo a series of transformation which is called biotransformation. This process alters the lipophilic drugs to a polar object i.e. hydrophilic and is readily absorbed by body. With the addition of functional group in the 1st phase which included oxidization, reduction, hydrolysis etc. Than by undergoing synthetic phase i.e. addition of endogenous compounds, which make them readily absorbed. While most of the drug metabolism is carried out in liver, some tissues, intestine also have enzymes to undergo the process.
Scientific journal is a periodical publication intended to further progress of science, usually by reporting novel research. There are thousands of scientific journals in publication, and many more have been published at various points in the past. Most journals are highly specialized, although some of the oldest journals publish articles and scientific papers across a wide range of scientific fields. Scientific journals contain articles that are peer reviewed, to ensure that articles meet the journal's standards of quality, and scientific validity. The publication of the results of research is an essential part of the scientific method. If they are describing experiments or calculations, they must supply enough details that an independent researcher could repeat the experiment or calculation to verify the results. Each such journal article becomes part of the permanent scientific record.
Last date updated on April, 2024