There are 3 branches chain amino acids that are Isoleucine(I), Leucine(L)and Valine (V) that highly effective in stimulating the growth skeletal muscle via protein synthesis.Leucine has much greater power on stimulating protein synthesis compared to any other amino acid. One of the most researched pathways of muscle growth is called the mTOR pathway (mechanistic target of rapamycin), and leucine activates complex muscle-building pathways via mTOR. 1,2 In fact, mTOR is highly sensitive to concentrations of leucine.
If leucine levels declines signal mTOR that there's a lack of dietary protein present to synthesize new skeletal muscle protein, therefore disabling mTOR. Upon ingesting increased concentrations of leucine, the elevated amino acid then signals mTOR that sufficient dietary protein exists, and switches on overall protein synthesis. An important point to remember is an increase in mTOR activity (and all aspects of the pathway with which it belongs) results in an increase in protein-building and more growth.
Let us switch to supplementing to Leucine amino acid and have growth in short span to time. Any more related interesting articles please log on to Journal of Proteomics & Bioinformatics