Rheumatic heart disease is caused on account of a series of rheumatic fever that occurs due to the functioning effect of various genes related with the biological processes. This disease is also related to the autoimmune reactions occurring in the human body. Several HLA class II alleles have been associated with the disease. In the present article, a review of the effects of all the genes that are involved in innate as well as adaptive immunity on the body. On account of more information about these effects, a safer vaccine can be developed thereby helping us to reduce the probability of occurrence of the disease.
For information regarding this article, kindly visit to the link https://www.omicsonline.org/rheumatic-heart-disease-genes-inflammation-and-autoimmunity-2161-1149.S4-001.pdf
For citing the article, please see: Guilherme L, Köhler KF, Kalil J (2012) Rheumatic Heart Disease: Genes, Inflammation and Autoimmunity. Rheumatol Curr Res S4:001. doi:10.4172/2161-1149.S4-001