alexa Neuromyelitis Optica Spectrum Disorder

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Neuromyelitis Optica Spectrum Disorder

Transverse myelitis (TM) is an inflammatory demyelinating disorder of the spinal cord that has various manifestations. TM has several subtypes according to origin but, in China, most of them are associated with neuromyelitisoptica (NMO) and multiple sclerosis (MS).NMO immunoglobulin G (IgG), selectively targeting to the antigen of aquaporin-4 (AQP4) that localizes in the central nervous system (CNS) microvessels, pia, subpia, and Virchow-Robin space has been considered as an biomarker to some TM.which is defined as NMO spectrum disorder (NMOSD). Previous studies have revealed this autoantibody as an important contributor to TM pathology.


Citation: Shan F, Long Y, Fan Y, Chen M, Zheng Y, et al. (2014) Neuromyelitis Optica Spectrum Disorder and Neurosyphilis Coexist in A Chinese Woman . J Mol Biomark Diagn 5:198.

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