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Both innate and adaptive immune responses play a central role in fighting off infection. The innate production of proinflammatory cytokines and interferon type (IFN) I and II secretion are central to activating adaptive immunity. The cell types associated to innate immune responses include macrophages, monocytes, natural killer (NK) cells and dendritic cells as well as non haemopoietic cells such as hepatocytes. Innate immunity begins when pathogen recognition receptors (PRRs) detect viral infection. For more details:
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