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Clinical Relevance of Pharmacogentic Testing: Clinical vs. Ethical

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Clinical Relevance of Pharmacogentic Testing: Clinical vs. Ethical

“Variability is the law of life and as no two faces are the same, so no two bodies are alike, and no two individuals react alike and behave alike under abnormal conditions which we know as disease.” [1]. The study of pharmacogenetics serves to explain variability in pharmacological response resulting from genetic differences. Pharmacogenetics is based on the observation of phenotypes and investigates variations in genes as they relate to drug metabolism. It allows for better comprehension of pharmacodynamics and pharmacokinetics in order to reduce potentially harmful side effects [1]. The mainstay of pharmacotherapy involves giving the right medication at the right dose to the right patient in order to treat a specific disease state or condition. Personalized medicine is achieved through having a comprehensive understanding of how a drug works, the pathology of the disease state, and drug response within individuals.

For more details: Shawaqfeh MS (2014) Clinical Relevance of Pharmacogentic Testing: Clinical vs. Ethical. J Pharma Care Health Sys S1-e001. doi: 10.4172/2376-0419.S1-e001

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