The functional impairment of bone marrow derived endothelial progenitor cells remains an important barrier for cardiac cell-based therapies. Our aim was to create a relevant swine model of chronic ischemia and document its effect on bone derived progenitor cells.
Maltais S, Haglund NA, Tanguay JF, Sirois MG, Tardif JC, et al. (2011) Functional Exhaustion of Bone Marrow Derived Endothelial Progenitor Cells in a Chronic Swine Model of Myocardial Ischemia. Autacoids S3:002. doi:10.4172/2161-0479.S3-002