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Malassezia are common lipiddependent fungi that grow on the sebaceous areas of human skin, including the face, scalp, and upper trunk. Although Malassezia are a part of the normal human skin flora, they may also cause or exacerbate several skin diseases, including tinea versicolor, Pityrosporum folliculitis, and seborrheic dermatitis. Topical antifungals are the mainstay of treating Malassezia-related diseases. Chronic prophylaxis is often required to prevent recurrences. Malassezia are lipophilic (lipid-dependent) fungi that compose part of the normal human skin flora, but are now also recognized to play a role in skin disease. Malassezia have clearly been shown to be the causative organism in tinea versicolor and Pityrosporum folliculitis, and are likely to play a role in seborrheic dermatitis (Gupta, Batra, Bluhm, Boekhout, & Dawson, 2004). Evidence for their involvement in other skin conditions, including atopic dermatitis, psoriasis, and neonatal cephalic pustulosis, is weaker.