alexa Adult Acute Biphenotypic Leukemias

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Adult Acute Biphenotypic Leukemias

Acute leukemias (AL) are classified as myeloblastic or lymphoblastic, basing on blasts origin from appropriate cell line. In the French-American-British (FAB) classification combination of morphological and cytochemic staining of blast cells was sufficient to classify most of the acute leukemias. Advancement of knowledge and, above all, introduction of monoclonal antibodies in the widespread use of flow cytometry revealed that part of acute leukemias has the characteristics of both myeloid- and lymphoid- leukemia, and another part it is still difficult to define. This was reflected in the classification of the World Health Organization, which among this group of diseases distinguished undifferentiated leukemia, bilinear leukemia and biphenotypic leukemia.

 

Citation: Butrym JA, Rybka J, Jurczyszyn A, Dybko J, Kujda DU, et al. (2015) Adult Acute Biphenotypic Leukemias: Polish Single Centre Experience. J Mol Biomark Diagn 6:209

 
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