Rhenium-188 is an important beta-gamma emitter, which emits beta particles with an average energy of 784 keV and a maximal energy of 2.11 keV as well as gamma photons with energy of 155 keV (15%) and a half-life time of 17 hours. There are important properties which make this radioisotope of interest for clinical use. A number of important therapeutic applications of rhenium-188, which have been developed over the two decades, have demonstrated uses of rhenium-188 as a cost effective alternative to more expensive and/or less readily available therapeutic radioisotopes. A radiometric characteristic of radiation emitted by Rhenium-188 creates advantageous conditions for medical applications of this radionuclide. The Radioisotope Center Polatom Poland has developed and implemented the technology for routine production of carrier free 188Re. The radionuclide generator is an efficient and convenient device for obtaining 188Re solution.