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Possible Mechanism of Action of the Hypotensive Effect of Peperomia pellucida and Interactions between Human Cytochrome P450 Enzymes

Hypertension is a major cardiovascular burden that has been estimated to cause 7.1 million premature deaths and 45 % of the disease burden. However, it remains inadequately managed everywhere, and in spite of the large number of antihypertensive medications, most people in developing countries have poor access to modern health-care and cannot afford these drugs due to cost. Therefore, they resort to alternative herbal remedies to manage hypertension.Such alternative remeadies include the use of herbs and natural plant products, one of the plant used is Peperomia pellucid. Peperomia pellucida is a common, fleshy annual herb that belongs to the family of Piperaceae. It is commonly called shiny bush, pepper elder, man-to-man, rat-ear, Pansit pansitan and is found mainly in the tropics.

 

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Medicinal & Aromatic Plants

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