Extension of the Membranes as Metabolic Pacemakers Theory to Fowl Species and their Metabolically Active Tissues
Biological membranes, made-up basically by Phospholipid (PL) bilayers are the basis of cellular organization. In 2007 Hulbert et al. reviewed the mechanism underlying their regulatory role; in particular how membrane integrated Fatty Acyl (FA) chains modify Basal Metabolic Rate (BMR). On a cellular level BMR involves synthetic processes and the maintenance of trans-membrane ion gradients. The molecular activity of transmembrane (e.g. Na+/ K+ ATPase) enzymes is likewise determined or markedly influenced by the physico-chemical properties of the surrounding membrane lipids, thus, membranes have postulated to act as “pacemakers of the metabolism”. As body mass and BMR are allometrically related, membrane fatty acyl chain composition and body mass are also related allometrically in homeothermic species. READ..