Erythrokeratoderma or erythrokeratodermia, is an uncommon gathering of clutters of keratinisation. This is the process that structures the distinctive layers of the epidermis, the furthest layer of the skin. The different erythrokeratodermas are described by overall divided plaques of erythema (redness) and hyperkeratosis (scaling). Erythrokeratoderma is diagnosed by its clinical appearance. Skin biopsy might be performed for histology yet there are no different peculiarities. Hereditary directing ought to be offered to influenced people and their groups of childbearing age. There is no particular or therapeudic treatment. Minimizing temperature changes and mechanical erosion is vital. Symptomatic change might be acquired by Emollients, Keratolytics, for example, urea, salicylic corrosive or alpha hydroxy acids, Topical steroids Topical retinoids, Oral retinoids, for example, acitretin or isotretinoin. These slender down the plaques and diminish scaling however the redness holds on.