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In Parkinson’s disease (PD), the activity of AADC in the striatum is reduced to 5%–20% of normal levels before cardinal motor symptoms become apparent. High-resolution FMT-PET images can clearly demonstrate a reduction of the subregional AADC activities, and the lowest FMT uptake values tend to be observed in the posterior part of the putamen contralateral to the more affected limbs, even in the early stage of the disease. This case therefore demonstrated the diagnostic value of using FMT-PET in the diagnosis of mild PD, particularly when encountering patients that do not show any remarkable tremors while at rest.
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