In breast cancer patients whose breast cancer has spread to their lymph nodes have most of the lymph nodes in their armpit area removed after chemotherapy to see if any cancer remains. Minimal invasive protocol sentinel lymph node is suitable for individuals to identify the cancer cells remained after chemotherapy before breast surgery. In this protocol the particular cells which were identified can be removed. Axillary lymph node status which is an important prognostic factor in breast cancer, accurate determination of axillary involvement after chemotherapy is much considered. By removing all axillary nodes to assess for residual nodal disease which exposes many patients to potential side effects of breast surgery, which avoid the complications associated with axillary lymph node dissection, it is preferable to identify nodal disease with the less invasive sentinel lymph node surgical procedure, resulting in fewer side effects. Sentinel lymph node surgery diagnosed accurately. The false-negative rate is more than 10% which is much lesser than other diagnosis techniques After chemotherapy the individuals who undergone both sentinel lymph node surgery and axillary lymph node surgery experience side effects in which the outcome of side effects were considered less and diagnosis were accurate.