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Meningeal cells influence midbrain development

Dopaminergic neuroblasts, sequestered from ventral midbrain fetal tissue, have been presented to structurally and functionally integrate, and improve Parkinsonian symptoms following transplantation. The use of donor tissue isolated at an age younger than conventionally employed can outcome in larger grafts - a consequence of enhanced cell survival and neuroblast proliferation at the period of implantation.

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