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Large amounts of dyes are annually produced and applied in many different industries, including textiles, cosmetics, paper, leather, pharmaceutical and food. The three most common groups are azo, anthraquinone and phthalocyanine dyes. Most of these dyes are toxic and carcinogenic. Disposal of these dyes into the environment causes serious damage, since they may significantly affect the photosynthetic activity of hydrophytes by reducing light penetration and also they may be toxic to some aquatic organisms due to their breakdown products. The degradation of azo dyes produces aromatic amines, which are carcinogenic, and mutagenic. Recently, several reports appeared showing that the microorganism has ability, not only to decolorize dyes but also detoxify it.