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In children undergoing open appendectomy, single-dose levobupivacaine + morphine mixture via caudal route is a simple, safe and efficient method for post-operative analgesia. Quality of postoperative pain management might decrease due to nausea-vomiting after day-case surgery even though analgesia was excellent. Besides, morphine is not suitable for day-case surgeries because of late respiratory depression due to rostral progression. The patient group which we have investigated was consisted of children who were treated a few days in pediatric surgery unit. Single dose caudal levobupivacaine plus morphine combination provides a simple, safe and effective postoperative analgesia for pediatric open appendectomies.