alexa Immune Response Modulation by Tumor-Secreted Glycosphingolipids

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Immune Response Modulation by Tumor-Secreted Glycosphingolipids

Although originally considered merely structural components of cellular membranes, glycosphingolipids (GSL) are now recognized as having critical effects on cellular physiology, including proliferation, differentiation, viral transformation and ontogenesis. In addition, a vast majority of human cancers have modified GSL composition compared to parental normal cells. These modifications may contribute to both tumor survival and exert striking effects on anti-tumor immunity. In this review, we discuss mechanisms of immune modulation by tumor-secreted GSL.

 

Citation: Lardone RD, Cely I, Sieling PA, Lee DJ (2014) Immune Response Modulation by Tumor-Secreted Glycosphingolipids. J Glycobiol 3:107. doi: 0.4172/2168-958X.1000107

 
  • Share this page
  • Facebook
  • Twitter
  • LinkedIn
  • Google+
  • Pinterest
  • Blogger