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Low calorie low cost xylitol, a natural five carbon sugar-alcohol, is known to be affecting the genetic continuity of Streptococcus pneumoniae (causing pneumonia) and important members of the viridans group streptococci, including S. mutans (involved in dental caries), S. mitis (associated with bacteremia, meningitis, periodontal disease and pneumonia). These pathogens have similar diplococcic morphology and it is known that Streptococcus mitis bacterial species has several similar physiological characteristics common to S. pneumoniae including the ability to partially metabolize xylitol to produce a toxic xylitol intermediate, probably xylitol-5- phosphate.
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