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Living Donor Transplantation of Kidneys with Fibromuscular Dysplasia: Indications, Surgical Techniques and Long Term Results in 11 Cases

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Living Donor Transplantation of Kidneys with Fibromuscular Dysplasia: Indications, Surgical Techniques and Long Term Results in 11 Cases

"Due to the limited availability of organs for transplantation, the criteria for the acceptance of donor kidneys have been extended to include donations from expanded criteria donors either Deceased Donors (DD) or Living Donors (LD). The presence of Fibromuscular Dysplasia (FMD), an arterial disorder characterized by “string-of-beads”of the renal artery, was one of the abnormalities which had previously excluded the acceptance of the potential donors. The incidence of FMD in potential LDs is observed in a range from 2% to 6.6% with a female predominance; it is the second most common anatomical abnormality after multiple renal arteries. FMD still represents a challenge for any decision to harvest the kidney, particularly from a LD, due to the potential risk to develop a renovascular hypertension and/or FMD either in the remnant kidney after donation or in the recipient’s graft. Moreover, the problem may only arise at the operative stage since early forms of FMD give rise to no or mild radiographic evidence. This ‘mild’ radiographic evidence has been described by Indudhara as irregularity of the arterial wall without significant stenosis. 

For full article https://www.omicsonline.org/living-donor-transplantation-of-kidneys-with-fibromuscular-dysplasia-indications-surgical-techniques-and-long-term-results-in-11-cases-2161-0959.S4-008.php?aid=9224 "

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