Ankylosing Spondylitis is an immune disease. Ankylosing Spondylitis mainly affects spine and later other joints involves. Most often, ankylosing spondylitis affects men when compared to women. Although it can occurs at any stage, strikes men in their teenage and in 20’s. There is no cure for ankylosing spondylitis, but treatments can decrease your pain and lessen your symptoms. The diagnoses are done by several factors: 1. Symptoms. 2. Physical exam done by doctor. 3. X-rays. 4. Measurement of the chest when breathing.