The incidence of primary tumors that metastatisize to the orbit is approximately 7%. The most common malignant primary tumors in adults metastasizing to the orbital are breast cancer (42%), lung (11%), unknown primary (11%), prostate (8.3%), melanoma (5.2%), gastro-intestinal tract (4.4%) and kidney cancer (3.2%). Orbital metastases spread hematogenously, as there are no significant lymphatics in the orbit. The median survival after diagnosis of orbital metastasis has been reported to be approximately 9 months. In 19% of the cases, there is no history of cancer when the patient presents ophthalmic symptoms. Unilateral ptosis due to orbital metastases is rarely the first sign of lung cancer.
Citation: Resuli B, Lisi R, De Felice F, Musio D, Tombolini V (2014) Hypofractionated Stereotactic Radiotherapy for Orbital Metastases: A Case Report and Review of Literature. J Cytol Histol 5:273.