Systemic Lupus Erythematosus is an autoimmune disease. It has various characteristics that are categorized as complications in the human body. It is mainly affected due to genetic, environmental and hormonal factors. It has been categorized by the presence of various pathogenic autoantibodies as well as inflammatory reactions in the body. These autoantibodies are produced by abnormally self reacting B-cells. These B cells do not get matured in the presence of SLE. Their activation is promoted by B-cells Activating factors which get reduced when the patient is associated with SLE. For more information about the article, kindly follow the link.