alexa Epigenome Research of Stem Cell and Tumorigenesis

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Epigenome Research of Stem Cell and Tumorigenesis

Epigenome contains another layer of genetic information, not as stable as genome. Dynamic epigenome can serve as an interface to explain the role of environmental factors. Stem cell and tumorigenesis are reported to be closely associated with epigenome modifications. Next generation sequencing (NGS) technologies have directly leaded to the recent advances in epigenome research of stem cell and cancer. DNA methylation and histone modification are two major epigenetic modifications.

Citation: Li J, Wang T, Zhang X, Yang X (2011) The Contribution of Next Generation Sequencing Technologies to Epigenome Research of Stem Cell and Tumorigenesis . Human Genet Embryol S2:001.

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