alexa Establishing Genome Sequencing Centers

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Establishing Genome Sequencing Centers

In an effort to scientifically pinpoint the impact of radio- nucleotide on humans, after the use of atomic bomb by July 16, 1945 at Alamogordo, Mexico, Hiroshima and Nagasaki, Japan by August 1945; through the act of United States congress, the U.S. Department of Energy [1] was asked to study and analyze the genomic structure, replication, damage and repairs and the consequences of genetic mutation especially those caused by radiation and chemical by-products of energy production. From the plethora of scientific studies emanating from this official investigation grew the recognition that the most ingenious way to study the effects of radio-active agents on humans was to analyze the entire human genome to enable scientists have access to a reference genome [1,2,3]. Although planning began in 1986, regarding the Department of energy's human Genome Program, the National Institutes of Health (NIH) got involved in 1987. The joint initiative between The DOE-NIH, United States led Human genome Project formally began by October 1, 1990. The memorandum of Understanding was signed after the first joint 5-year plan was documented between the two United States federal scientific organizations. The accomplishment of human genome sequencing, mapping and declassification is practically incomplete without the imaginative vision of The Nobel laureate Dr. James D. Watson and his colleagues. In 1986, Dr Watson organized a special session to discuss the full ramifications of the human genome project, during that meeting at Cold Spring Harbor Laboratory, the idea was raised by Wally Gilbert that the project could consume a colossal sum of money to the tune of "3 billion base pairs, 3 billion dollars". This was perceived as an extremely expensive project that could only succeed with public funding. The role of Dr. Watson and his associates [4] in involving political leaders and soliciting funding for the accomplishment of the HGP can hardly be overemphasized. As the first biologist to serve as the director of the human genome unit at the National Institutes of Health, he cautioned both administrators and scientists about the enforcement of sanctimonious ethical principles in the practical implementation of genomics; discouraging the slightest elements of eugenics in the existing guidelines and protocol of conducting genomic research nationwide and internationally [3,4]. Currently even the comprehensive data on human genome is completely declassified and placed under public domain.

Citation: Ebomoyi EW (2011) Establishing Genome Sequencing Centers, the Thematic Units in the Developing Nations and the Potential Medical, Public Health and Economic Implications. J Drug Metab Toxicol 2:108. doi: 10.4172/2157-7609.1000108

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