An outlier is a scientific term to describe things or phenomena that lie outside normal experience. In pharmacokinetics this would be a parameter such as drug clearance or half-life that has a value that is much different from the average. Patients with pharmacokinetic parameters that are outliers are often the most difficult to manage. Identifying the reasons for being an outlier has always been a goal in the field of pharmacokinetics/pharmacodynamics.
Citation: Slaughter RL (2012) Outliers: The Case for Individualized Therapy. Adv Pharmacoepidem Drug Safety S1:e001. doi: 10.4172/2167-1052.S1-e001