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The definition physiological accessibility can be presented by the following formula: PhA = C/Sx100 %, Where: PhA-physiological accessibility; C-quantity of substance with action pharmacological absorbed after prescription of the investigated pharmacological form; S-quantity of the substance with action pharmacological, which have absorbed after prescription of the standard pharmacological form. The measuring of biological availability may be represented by the following formula: BA = C/S x 100 %.