Over the past decades, Japan has experienced several drug-induced disasters, and so, the improvement in drug safety measures containing risk communication has become an important issue . In Japan, Risk Management Plan (RMP) has begun in April, 2013 which is seven years behind as compared to the most Western countries. RMP consists of three elements: Safety Specification, Pharmacovigilance (PV) Plan and Risk Mitigation Plan. Although the drug companies undertake the duties for RMP, the pharmacists in the clinical spots are expected to take part and contribute to RMP more actively. In order to meet the expectation, systematic learning of the framework, structure, and view of drug safety in the clinical education at undergraduate level of pharmacy is essential.