In this study, we found that the amount of isoflavones in (1) steaming germinated soybean was higher than that of (2) soybean boiled in water and (3) steamed soybean. Moreover, genistein, a major soy isoflavone, selectively inhibited the activity of human topo II. Therefore, steaming germinated soybean, which has high amount of genistein, might be a cancer preventive food through the inhibition of topo II activity.
Citation: Kuriyama I, Yoshida H, Mizushina Y, Takahashi Y (2013) Inhibitory Effect of Isoflavones from Processed Soybeans on Human DNA Topoisomerase II Activity. J Plant Biochem Physiol 1:106. doi: 10.4172/2329-9029.1000106