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Bubble column reactors are widely used in chemical and biochemical processes such as oxidation, chlorination, polymerization, hydrogenation, synthetic fuels by gas conversion processes, fermentation and wastewater treatment. Bubble columns can be employed in many mass transfer processes. However, the lack of a more complete knowledge on the bubble column fluid dynamic behavior in its various regimes causes several operational difficulties and design uncertainties, which include poor predictions of the mean bubble diameter, gas hold up and interfacial area.