Innovations in Gas Chromatography (GC) and Mass Spectrometry (MS) instrumentation from a variety of scientists working in the public and private sectors of research and development have driven this traditional two-dimensional hyphenated technology, and/or recently three- and four-dimensional hyphenated technologies in the case of a second GC and/or a MS equivalent being added, to become one the dominate platforms for use in a wide assortment of analytical and bioanalytical techniques. The analysis of drugs, metabolites, pesticides, chemical warfare agents, food ingredients, medications, fuels, and etcetera and/or in the main category of volatile and semi-volatile organic compound analysis in fields such as forensic, toxicology, environment, defense, food and beverage, pharmaceutical, petrochemical, and etcetera are all now considered to be growing in size and in scope in the use of GC-MS instrumentation. The advancement in GC-MS instrumentation was initially and still is driven by the need for a more comprehensive analytical and bioanalytical technique that can accurately and precisely discriminate targeted and untargeted analytes from higher complexity sample mixtures in a sensitive and selective way. To that end, this review, like the preceding review on LC-MS, will briefly attempt to focus on the most current emerging trends in GC-MS instrumentation and their respective contributions to the field of analytical and bioanalytical techniques.
Citation: Steiner WE, English WA (2015) Emerging Trends in Gas Chromatography and Mass Spectrometry Instrumentation for Analytical & Bioanalytical Techniques. J Anal Bioanal Tech 6:e118. doi: 10.4172/2155-9872.1000e118