alexa Role of Cell Wall Polysaccharides during Recognition of Candida albicans by the Innate Immune System

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Role of Cell Wall Polysaccharides during Recognition of Candida albicans by the Innate Immune System

Candida albicans is a dimorphic fungus that normally colonizes mucosal tissues, forming part of the microflora. Its population is normally controlled by the mucosal microenvironment and the bacterial flora; although changes in any of these factors may lead to fungal overgrowth and tissue damage. The host immune system is capable to control such infection, and in immunocompetent patients the disease is restricted to superficial tissues. However, when the host experiences a temporal or permanent immunosuppression the fungus has the potential to cause systemic infections that are associated to high mortality rates

 
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