The original concept of ‘the memory of water’ was based on water clusters serving as information carriers. However, it showed that hydrogen bonds in these clusters have too short a lifetime to hold information. To meet this objection proposed the existence of nano domains in water, formed as a result of a mechano-chemical effect such as the vigorous shaking that is part of the homeopathic process. Such nano domains may be produced by groups of synchronously vibrating bonds in water molecules losing their vibration energy in the process of breaking an OH-bond. The bond breaking generates H- and OH-radicals, each containing a radical electron in the triplet excited state and exploited the suggestion of that two triplet excited states participate in an energy transfer, with one triplet becoming a single excited state and the other returning to the ground state.