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Although small non-coding RNAs, particularly microRNAs (miRNAs), small interference RNAs (siRNAs), and piwiinteracting RNAs (piRNAs), account for only a minor fraction of the expressed genome, they have been recognized as important regulators of gene and genome at post-transcriptional levels, functioning as RNA interference (RNAi) to regulate some of the most important biological processes in eukaryotic cells.
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