A case of persistent influenza AH1N1 and cytomegalovirus respiratory infection in a patient with chronic interstitial lung disease and multiple bilateral pulmonary opacities has been observed. An open lung biopsy revealed diffuse organizing alveolar damage, necrotizing bronchiolitis, necrotizing pneumonia and alveolar hemorrhage, compatible with H1N1 infection as well as usual interstitial pneumonia. Diagnoses of an idiopathic CD4+ T cell lymphocytopenia and immunoglobulin G deficiency were made as an unexpected co-denominator of H1N1 and CMV persistent infection changing our treatment approach.
Valente Barbas CS, Rocha LL, de Matos GJF, Lomar FP, Shiang C, et al. (2013) Acute Respiratory Failure in Idiopathic Pulmonary Fibrosis: Co- Infection With H1n1 And Cytomegalovirus: An Unexpected Common Denominator. Emergency Med 3:152. doi: 10.4172/2165-7548.1000152