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Delusional infestation (DI) is a type of monosymptomatic hypochondriacal psychosis characterized by the steadfast belief that one is infested with living organisms or inanimate material in the absence of objective proof. Although DI is generally regarded as a single psychotic phenotype characterized by either the presence or absence of a delusion, our experience has been that patients with DI present with varying levels of severity represented by various phenotypes along a continuum. Delusional infestation (DI), also known as delusions of parasitosis, is a type of monosymptomatic hypochondriacal psychosis characterized by the false yet steadfast belief that one is infested with living organisms or inanimate material. Although DI is generally regarded as a single psychotic phenotype characterized by either the presence or absence of a delusion, the variability in delusional beliefs regarding the source of infestation was recently described to represent a heterogeneous diagnostic group of patients.
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