Biological safety has been recognized as an important topic for a long time. Since the 1983 WHO I-st edition of the “Laboratory biosafety manual”, a continuous effort for the implementation of basic elements and notions regarding biological safety led to national codes of laboratory practice for the safe manipulation and processing of pathogenic microorganisms and for potentially contaminated biological products.Microbial taxonomy has been constantly readjusted following the develpoment of techniques and equipments. New clinical entities were discovered and described as “emergent infectious diseases”. Also, the epidemic dimension and clinical evolution of some communicable diseases have been marked by important changes; this led to these diseases being labeled as “reemergent”. Together with newly discovered/ re-classified microorganisms, the phenomenon of increased antibiotic resistence is generating problems all over the world.
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