Multiple sclerosis (MS) is a chronic and putatively immune mediated inflammatory disease of the central nervous system. It is characterized by the damage of fatty myelin sheaths around the axons of the brain and spinal cord, leading to demyelination and scarring as well as a broad spectrum of signs and symptoms . Apitherapy is the medical use of honey bee products. This includes the use of honey, pollen, bee bread, propolis, royal jelly, and apilarnil and bee venom. Most claims of apitherapy have not been proved to the scientific standards of evidence-based medicine and are anecdotal in nature. Bee venom therapy is an alternative form of healing. Bee venom therapy is the part of apitherapy which utilizes bee venom in the treatment of health conditions. Bee sting therapy is increasingly used to treat patients with MS in the belief that it can stabilize or ameliorate the disease. However, there are no clinical studies to justify its use.