Human body is poised of closely 104 cells. Every day billions of cells are formed by mitosis and a similar number of cells decease by apoptosis to preserve tissue homeostasis. Biological cell death happens when a cell inside an organism dies by a contrivance orchestrated by proteins encoded by the host’s genome. Apoptosis refers to both the beginning and killing of the actions whereby a cell constrains suicide and it is different from other forms of cell death. It is a course of meticulous cellular death whereby the initiation of specific death-signaling pathways leads to removal of cells from tissue. It affords a proficient mechanism of eliminating unwanted cells during normal embryonic and adult development. Biologically, all multicellular organisms use apoptosis during development, homeostasis, defense, metamorphosis, terminal differentiation, immune response, cellular response to growth factors and hormones.