African trypanosomosis is a protozoan disease. It is caused by trypanosomes and transmitted by tse tse fly. Although Trypanosoma rhodiense and Trypanosoma gambiense cause African Human Trypanosomosis (AHT, sleeping sickness), Trypanosoma brucei brucei, Trypanosoma vivax, Trypanosoma congolense, Trypanosoma evansi and Trypanosoma equiperdum are the agents of African Animal Trypanosomosis (AAT). The economic impacts of trypanosomosis in Africa are various and intricate, with direct effects on animal production and human health, as well as indirect effects on settlement patterns, land use, animal husbandry and farming. AAT is associated with fever, depression, weakness, anemia, salivation, lacrimation, nasal discharges, and subcutaneous edema of the mandible and prominent jugular pulse. The appetite is decreased and there is a rapid weight loss which progresses to an extreme emaciation. Often, death is related to severe anemia and circulatory collapse.