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Purpose of this study is to evaluate the extent to which participation in a peer-led educational program about substance abuse produces changes in knowledge and attitudes among Lebanese/Armenian adolescents. Methods: a quasi-experimental study. A convenient sample 134 high school students, from two Armenian high schools in Beirut were recruited. Design: Pretest-posttest; students completed a questionnaire before and one week after an educational program implemented by two peer-educators, who had participated in a 'training-trainees" project about prevention of substance abuse.