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Approximately 25% of patients with colorectal cancer have liver metastases at presentation and 50-60% of patients will develop liver metastases at some point. Without treatment, patients with liver metastases have an estimated overall survival of nine months. Surgical resection of the hepatic metastases has been shown to improve survival, however, only 20% of patients with liver metastases are amenable to surgical resection at presentation.
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